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Previous Volume 360:1577 April 9, 2009 Number 15 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Edited by Jennifer S. Hawkins and Ezekiel J. Emanuel. 327 pp. Princeton, NJ, Princeton University Press, 2008. $65 (cloth); $24.95 (paper). ISBN 978-0-691-12675-3 (cloth); 978-0-691-12676-0 (paper).

Clinical research in developing countries has generated considerable discussion. Especially controversial are the use of a placebo instead of the best proven treatment as a control, and the availability of a test intervention after the trial. That such designs, which would be rejected in the developed world, have been carried out in developing countries has led some to accuse the researchers involved of exploitation and to propose banning such trials.

This controversy stimulated a seminar series in the National Institutes of Health's bioethics department, which in turn resulted in this collection of essays. The writing style is consistently concise, the . . . [Full Text of this Article]

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