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A 36-year-old man was admitted to the hospital because of chest pain, dysphagia, dyspnea, and pleural and mediastinal calcifications.
He had been well until approximately 6 years before admission, when a 182-kg weight fell on his shoulders while he was lifting weights at a gym. Intermittent left-sided chest pain occurred thereafter, gradually increased in severity, and responded transiently to nonsteroidal antiinflammatory medications and ice packs. Two and a half years before admission, dysphagia developed in association with solid foods and gradually increased in severity to include liquids; he lost 4.5 kg in weight. An esophagogram reportedly showed minimal tertiary contraction
Differential Diagnosis
Systemic Disorders with Pleural Calcification
Diseases of the Chest Associated with Calcification
Parenchymal Lung Diseases
Mediastinal Diseases
Diseases of the Chest Wall
Non-Neoplastic Conditions
Osteosarcoma
Mesothelioma
Summary
Dr. Henning A. Gaissert's Diagnosis
Pathological Discussion
Anatomical Diagnoses
Source Information
From the Departments of Thoracic Surgery (H.A.G.), Radiology (N.P.), and Pathology (E.J.M.), Massachusetts General Hospital; and the Departments of Surgery (H.A.G.), Radiology (N.P.), and Pathology (E.J.M.), Harvard Medical School.
This article (10.1056/NEJMcpc0900637) was updated on October 7, 2009, at NEJM.org.
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