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Volume 360:1908-1910 April 30, 2009 Number 18
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Blood Oxygen on Mount Everest

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by Grocott, M. P.W.
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To the Editor: Grocott et al. (Jan. 8 issue)1 measured arterial blood gases in healthy climbers breathing ambient air on Mount Everest. The authors acknowledge the potential confounding influence of the subjects' use of supplemental oxygen before the sampling of blood gases, but further medication history is not provided. Apart from oxygen, a variety of medications, including acetazolamide, inhaled salmeterol, dexamethasone, sildenafil, and tadalafil, have been used by healthy climbers as prophylaxis against altitude-related illnesses.2 Use of these medications may affect the physiological response and subsequent blood gas values in hypoxic, hypobaric conditions, particularly with respect to the pulmonary vasculature . . . [Full Text of this Article]



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