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Volume 360:1925-1927 May 7, 2009 Number 19
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Does Comparative-Effectiveness Research Threaten Personalized Medicine?
Alan M. Garber, M.D., Ph.D., and Sean R. Tunis, M.D.

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The American Reinvestment and Recovery Act gives comparative-effectiveness research (CER) a large boost in funding over the next 2 years. Despite a consensus that better information about the relative effectiveness of different medical interventions is needed to improve the quality and value of care, some view CER with skepticism. Recently, the Partnership to Improve Patient Care, a coalition of 36 industry, patient-advocacy, and clinician organizations, raised concerns that CER will not take adequate account of individual patient differences and may impede the development and adoption of improvements in medical care and "stymie progress in personalized medicine."1

The controversy stems in . . . [Full Text of this Article]


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Dr. Garber is a staff physician at the Veterans Affairs Palo Alto Health Care System in Palo Alto, CA, and a professor of medicine, director of the Center for Primary Care and Outcomes Research, and director of the Center for Health Policy at Stanford University, Stanford, CA. Dr. Tunis is the founder and director of the Center for Medical Technology Policy, Baltimore.


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