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Volume 360:1927-1929 May 7, 2009 Number 19
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Debate about Funding Comparative-Effectiveness Research
Jerry Avorn, M.D.

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The proposal to include $1.1 billion for comparative-effectiveness research (CER) in the federal stimulus package encountered a vigorous and well-coordinated backlash. The campaign to gut this funding ultimately failed, but the debate it engendered and the resonance of the opposition's arguments in both lay and policy circles reveal much about the issues that will surround such research and its application in the coming years.

The contested provisions were designed to support studies comparing the efficacy and safety (and, by extension, the cost-effectiveness) of alternative ways of addressing common clinical problems. Interventions to be evaluated will include pharmaceuticals, devices, procedures, and . . . [Full Text of this Article]


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Dr. Avorn is a professor of medicine at Harvard Medical School, chief of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital, and director of the Harvard Interfaculty Initiative on Medications and Society — all in Boston.


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