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Previous Volume 360:2031-2032 May 7, 2009 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Reporting on the results of the Veterans Affairs Diabetes Trial (VADT), Duckworth et al. (Jan. 8 issue)¹ conclude that intensive glucose control in patients with poorly controlled type 2 diabetes had no significant effect on the rates of major cardiovascular events in their study.

In their discussion, the authors do not acknowledge that the assumptions of the prespecified analysis were not met. The observed event rate in the standard-therapy group was 33.5%, much lower than the predicted rate of 40.0%. Also, the observed dropout rate of 14% was much higher than the predicted rate of 5%. Given . . . [Full Text of this Article]

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