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Previous Volume 360:185-187 January 8, 2009 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The Understanding Potential Long-Term Impacts on Function with Tiotropium (UPLIFT) study by Tashkin et al. (Oct. 9 issue)¹ was expected to provide data on the effectiveness and safety of tiotropium in 5993 patients with chronic obstructive pulmonary disease (COPD). However, since the authors provide no information on the proportion of patients who started (or stopped) taking combined inhaled corticosteroids or long-acting beta agonists during follow-up, we do not know whether such a regimen may have confounded the study's findings. The benefit attributed to tiotropium might partly reflect concomitant use of other drugs. Also, it would be helpful . . . [Full Text of this Article]

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