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Editorial
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Volume 360:2127-2129 May 14, 2009 Number 20
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The ACTIVE Pursuit of Stroke Prevention in Patients with Atrial Fibrillation
Alan S. Go, M.D.

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 by The ACTIVE Investigators
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Approximately 1% of Americans have atrial fibrillation, and the prevalence of this arrhythmia increases sharply with older age (being approximately 10% among persons 80 years of age or older).1 Worldwide population trends of increasing life expectancy and increasing prevalence of selected risk factors for atrial fibrillation portend a worsening epidemic. Atrial fibrillation raises the risk of ischemic stroke by a factor of four to five, primarily as a result of cardioembolism of a fibrin-rich thrombus (Figure 1). Given the epidemiologic characteristics of atrial fibrillation and the importance of stroke as a leading cause of death and disability, multiple . . . [Full Text of this Article]


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From Kaiser Permanente of Northern California, Oakland.


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