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Editorial
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Volume 360:2353-2355 May 28, 2009 Number 22
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Radiofrequency Ablation — Great for Some or Justified for Many?
Jacques J.G.H.M. Bergman, M.D., Ph.D.

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by Shaheen, N. J.
-PubMed Citation
In the past four decades, the incidence of esophageal adenocarcinoma has increased by 500%, paralleled by a similar increase in the rate of death associated with this often fatal disease.1,2 This type of esophageal cancer develops from a precursor lesion known as Barrett's esophagus, a condition in which the normal squamous esophageal lining is replaced by columnar epithelium containing intestinal metaplasia. In a small subgroup of patients, Barrett's esophagus may undergo a transition from low-grade or high-grade dysplasia to esophageal adenocarcinoma.3

The current standard of care is to enroll patients with Barrett's esophagus in endoscopic surveillance programs and to surgically . . . [Full Text of this Article]


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From the Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam.



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