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Correction to Gnant et al., N Engl J Med 360(7):679-691 February 12, 2009.

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Volume 360:2367-2370 May 28, 2009 Number 22
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Endocrine Therapy plus Zoledronic Acid in Premenopausal Breast Cancer

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 by Gnant, M.
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To the Editor: Gnant et al. (Feb. 12 issue)1 report on the Austrian Breast and Colorectal Cancer Study Group trial 12 (ABCSG-12) (ClinicalTrials.gov number, NCT00295646 [ClinicalTrials.gov] ), which looked at the use of goserelin plus either tamoxifen or anastrozole with or without zoledronic acid in premenopausal women with breast cancer. The authors conclude that the addition of zoledronic acid improved disease-free survival and that treatment with tamoxifen and treatment with anastrozole were associated with similar rates of disease-free survival. However, a separate analysis of the group of patients who received anastrozole without zoledronic acid would be of interest.


Frederik Wenz, M.D.
. . . [Full Text of this Article]




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