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Previous Volume 360:2679-2680 June 18, 2009 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: With regard to the review article on primary open-angle glaucoma by Kwon et al. (March 12 issue),¹ we believe that some discussion of the possible role of vascular factors in the pathophysiology of glaucomatous optic neuropathy is necessary.

Investigators in the Barbados Eye Studies reported that baseline vascular risk factors, including decreased systolic blood pressure and decreased systolic, diastolic, and mean ocular perfusion pressure, can influence the risk of open-angle glaucoma. Specifically, low ocular perfusion pressure doubled the risk of glaucoma in that population.² Investigators in the Early Manifest Glaucoma Trial reported that baseline predictors of progression . . . [Full Text of this Article]

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