Reperfusion therapy has represented a great leap forward inthe management of myocardial infarction with ST-segment elevation.Its goal is early and complete recanalization of the infarct-relatedartery to salvage myocardium and improve both early and lateclinical outcomes. Complete reperfusion can be achieved witheither fibrinolysis or primary percutaneous coronary intervention(PCI), but with primary PCI the success rate is higher than90%, whereas current fibrinolytic therapy leads to full reperfusionin only 50 to 55% of recipients. Primary PCI, therefore, lookslike the most appropriate reperfusion tool, but there are substantiallogistic restrictions associated with it. The door-to-balloon. . . [Full Text of this Article]
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From the Department of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam.
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Routine Early Angioplasty after Fibrinolysis
Wilsmore B. R., Wilsmore A. D., Cooper H. A., Bogaty P., Brophy J. M., Hof A. v. t, Ottervanger J. P., Wang Z., Liang B., Mei Q., Cantor W. J., Goodman S. G., the TRANSFER-AMI Investigators , Verheugt F. W.A.
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N Engl J Med 2009;
361:1507-1510, Oct 8, 2009.
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This article has been cited by other articles:
Wilsmore, B. R., Wilsmore, A. D., Cooper, H. A., Bogaty, P., Brophy, J. M., Hof, A. v. t, Ottervanger, J. P., Wang, Z., Liang, B., Mei, Q., Cantor, W. J., Goodman, S. G., the TRANSFER-AMI Investigators, , Verheugt, F. W.A.
(2009). Routine Early Angioplasty after Fibrinolysis. NEJM
361: 1507-1510
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(2009). Fibrinolysis Before Angioplasty for ST-Segment-Elevation MI. Journal Watch Cardiology
2009: 1-1
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