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Volume 360:300-302 January 15, 2009 Number 3
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Drug-Eluting versus Bare-Metal Stents in Acute Myocardial Infarction

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by Mauri, L.
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To the Editor: Mauri et al. (Sept. 25 issue)1 report lower 2-year mortality rates among patients presenting in 2003–2004 with acute myocardial infarction who were selected for treatment with drug-eluting stents than among those selected for treatment with bare-metal stents. However, the fundamental question of causality between use of drug-eluting stents and mortality cannot be answered in this observational study. The rate of use of drug-eluting stents in the study was 55.6%, which is much lower than the national average of 90% in the same period.2 Although the recognition and avoidance of off-label use by academic cardiologists in Massachusetts may . . . [Full Text of this Article]



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