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Previous Volume 360:409-410 January 22, 2009 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Nearly one third of preschool children (4 years of age or younger) have intermittent wheezing, a condition that many of them outgrow. The most common early trigger is a respiratory virus infection, leading to a pattern of episodic wheezing, with no symptoms between viral infections. Some children, particularly those with atopy, have a different clinical phenotype known as "multitrigger" wheezing. This condition is characterized by wheezing after exposure to multiple triggers, such as exercise and exposure to smoke, allergens, or cold air, as well as viral infections.¹

The distinctions among types of wheezing are not fixed. For example, an 18-month-old . . . [Full Text of this Article]

Source Information

From the Imperial School of Medicine at the National Heart and Lung Institute and the Royal Brompton Hospital, London.

Related Letters:

Oral Corticosteroids in Children with Wheezing
Koumbourlis A. C., Weinberger M., Ducharme F. M., Zemek R. L., Schuh S., Mroueh S., Walter A. W., Lambert P., Grigg J., Bush A.
Extract | Full Text | PDF  
N Engl J Med 2009; 360:1673-1676, Apr 16, 2009. Correspondence

This article has been cited by other articles:

• Axelsson, I. (2009). Oral prednisolone did not improve outcomes in preschool children with an attack of wheezing. Evid. Based Med. 14: 77-77 [Full Text]  
• Koumbourlis, A. C., Weinberger, M., Ducharme, F. M., Zemek, R. L., Schuh, S., Mroueh, S., Walter, A. W., Lambert, P., Grigg, J., Bush, A. (2009). Oral Corticosteroids in Children with Wheezing. NEJM 360: 1673-1676 [Full Text]  
• Bush, A. (2009). Update in Pediatric Lung Disease 2008. Am. J. Respir. Crit. Care Med. 179: 637-649 [Full Text]  
• (2009). Treatment for Children with Viral-Induced Wheeze. JWatch Pediatrics 2009: 1-1 [Full Text]