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Previous Volume 360:544-546 January 29, 2009 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Atypical hemolytic–uremic syndrome of infancy is a rare disorder that is associated with thrombotic microangiopathy and acute renal failure. It often involves complement dysregulation.^1,2 Plasma infusions have variable efficacy, and end-stage renal disease often develops in children who are unresponsive to plasma therapy.^1,2 We report on a patient with congenital relapsing atypical hemolytic–uremic syndrome who was unresponsive to plasma therapy but had a response to eculizumab, a humanized monoclonal antibody against terminal complement protein C5.³

An 18-month-old boy was admitted with a fourth relapse of congenital atypical hemolytic–uremic syndrome. He was born at 34 weeks' gestation, and . . . [Full Text of this Article]

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More on Eculizumab for Congenital Atypical Hemolytic–Uremic Syndrome
Shin J. I., Lee J. S., Gruppo R. A.
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N Engl J Med 2009; 360:2142-2143, May 14, 2009. Correspondence

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