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A 51-year-old woman presented with a 3-month history of fatigue and a 2-week history of a nonproductive cough and night sweats. Chronic myeloid leukemia was diagnosed, with a leukocyte count of 398,000 per cubic millimeter. On the basis of suspected leukostasis, sidestream dark-field (SDF) imaging was performed. SDF imaging is performed with a handheld microscope and the use of green light (530 nm) that is absorbed by hemoglobin to visualize the sublingual human microcirculation in real time. At the time of diagnosis, SDF imaging (Panel A and Video 1) showed abnormally large gaps between erythrocytes, probably because of leukocytosis . . . [Full Text of this Article] |
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