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Previous Volume 360:816-823 February 19, 2009 Number 8 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Economic globalization is an important development of the past half century. Proponents of globalization highlight the benefits of greater economic growth and prosperity; critics point to the exacerbation of economic disparities and the exploitation of workers, particularly in developing (i.e., low- and middle-income) countries.^1,2 Pharmaceutical and device companies have embraced globalization as a core component of their business models, especially in the realm of clinical trials. This phenomenon raises important questions about the economics and ethics of clinical research and the translation of trial results to clinical practice: Who benefits from the globalization of clinical trials? What is the potential . . . [Full Text of this Article]

Trends in the Globalization of Clinical Research

Ethical and Scientific Questions Raised by Globalization

Next Steps

Conclusions

Source Information

From the Duke Clinical Research Institute, Duke Translational Medicine Institute (S.W.G., J.G.M., E.D.P., C.B.C., R.A.H., R.M.C., K.A.S.), and the Department of Medicine (J.G.M., E.D.P., R.A.H., R.M.C., K.A.S.), Duke University School of Medicine, Durham, NC; and the Department of Emergency Medicine, University of North Carolina School of Medicine, Chapel Hill (S.W.G., C.B.C.).

Address reprint requests to Dr. Schulman at the Center for Clinical and Genetic Economics, Duke Clinical Research Institute, P.O. Box 17969, Durham, NC 27715, or at kevin.schulman@duke.edu.

Related Letters:

Ethical and Scientific Implications of the Globalization of Clinical Research
Adler J. R. Jr., Andrews C. A., Glickman S. W., Cairns C. B., Schulman K. A.
Extract | Full Text | PDF  
N Engl J Med 2009; 360:2792-2793, Jun 25, 2009. Correspondence

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