In the international SYNTAX trial, 1800 patients with three-vesselor left-main coronary disease were randomly assigned to eitherrevascularization with coronary-artery bypass grafting (CABG)or percutaneous coronary intervention involving drug-elutingstents. The need for repeat revascularization was significantlylower with CABG, but the risk of stroke was significantly higher— a tradeoff that must be considered in making clinicaldecisions regarding patients with advanced coronary disease.In a roundtable discussion moderated by Dr. Thomas Lee, cardiologistsDavid Hillis and Elizabeth Nabel debate the implications ofthese findings for clinical practice.
Smith, P. K.
(2009). Treatment selection for coronary artery disease: the collision of a belief system with evidence.. Ann. Thorac. Surg.
87: 1328-1331
[Full Text]
Smith, P. K.
(2009). Treatment selection for coronary artery disease: The collision of a belief system with evidence.. J. Thorac. Cardiovasc. Surg.
137: 1050-1053
[Full Text]