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A 56-year-old man with diabetes presented with a several-month history of decreased vision in the left eye. There was no history of trauma, flashes of light, or floaters. Visual acuity was 20/20 in the right eye and 20/200 in the left. Examination of the left eye revealed extensive retinal neovascularization (Panel A, arrowheads) superior to the optic disk (asterisk), as well as underlying retinal detachment (arrows). A monoclonal antibody against vascular endothelial growth factor was injected into the eye to reduce vascular proliferation before anticipated surgery. One week after a single intravitreal injection and 3 days before vitreous surgery, dramatic . . . [Full Text of this Article] |