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Editorial
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Volume 361:1897-1899 November 5, 2009 Number 19
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Innovation and Comparative-Effectiveness Research in Cardiac Surgery
Eric David Peterson, M.D., M.P.H.

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 by Shroyer, A. L.
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Cardiac surgery has always been a unique combination of art and science. The field is advanced by those who push the envelope by suggesting innovations. Yet promising techniques need to be rigorously evaluated before they are widely adopted. Coronary-artery bypass grafting (CABG) was pioneered in the 1960s and subsequently shown in a series of randomized studies to extend life and relieve angina in subgroups of patients with severe coronary disease.1 As a result of these studies, CABG has grown to become the most common surgical procedure in the world.2 During the subsequent years, however, CABG techniques have continued to be . . . [Full Text of this Article]


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From the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC.


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