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Correspondence
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Volume 361:202-206 July 9, 2009 Number 2
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Prostate-Cancer Screening

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 by Barry, M. J.
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 by Andriole, G. L.
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 by Schröder, F. H.
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To the Editor: The results of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Cancer Screening Trial (ClinicalTrials.gov number, NCT00002540 [ClinicalTrials.gov] ) by Andriole et al.1 were released prematurely, at the same time that Schröder et al.2 were reporting, on the basis of the European Randomized Study of Screening for Prostate Cancer (ERSPC) (Current Controlled Trials number, ISRCTN49127736 [controlled-trials.com] ), that screening with prostate-specific antigen (PSA) saves lives (March 26 issue). The PLCO trial is being portrayed as the underpinning for proposed changes in the mind-set of physicians and patients that prostate-cancer screening and treatment do more harm than good. However, the PLCO . . . [Full Text of this Article]




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