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Previous Volume 361:2097-2100 November 19, 2009 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Weinstein, J. N. Related Article by Buchbinder, R. Related Article by Kallmes, D. F. PubMed Citation

To the Editor: In the August 6 issue, Kallmes et al.¹ report on the Investigational Vertebroplasty Safety and Efficacy Trial (ClinicalTrials.gov number, NCT00068822 [ClinicalTrials.gov] ), and Buchbinder et al.² report on a randomized trial of vertebroplasty for painful osteoporotic vertebral fractures (Australian New Zealand Clinical Trials Registry number, ACTRN012605000079640). We have serious concerns about both trials, which included patients with a duration of pain of up to 12 months. Vertebroplasty provides internal fixation of nonhealed osteoporotic vertebral fractures. It is well established that fixation of acute fractures elsewhere in the skeleton reduces fracture pain. Internal fixation of healed fractures is clearly . . . [Full Text of this Article]

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• BOLSTER, M. B. (2010). Consternation and questions about two vertebroplasty trials. Cleveland Clinic Journal of Medicine 77: 12-16 [Full Text]