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Dr. Deborah L. Cummins (Dermatology): A 59-year-old man was seen by consultants in infectious disease and dermatology because of cutaneous and pulmonary lesions that developed after induction chemotherapy for acute myeloid leukemia.
A diagnosis of myelodysplastic syndrome had been made 13 months earlier at another hospital. Since that time, the patient had been hospitalized repeatedly elsewhere for pancytopenia and had received transfusions of red cells and platelets. (The results of laboratory tests obtained 12 weeks before admission to this hospital are shown in Table 1.) Six weeks before admission to this hospital, the patient received azacitidine subcutaneously, followed 15
Differential Diagnosis
Bacterial Infections
Invasive Fungal Infections
Approach to Diagnosis and Initial Therapy
Clinical Diagnosis
Dr. Thomas F. Patterson's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Division of Infectious Diseases, University of Texas Health Science Center at San Antonio, and the South Texas Veterans Health Care System (T.F.P.) — both in San Antonio; and the Departments of Dermatology (B.T.M.), Radiology (M.D.G.), and Pathology (A.P.), Massachusetts General Hospital and Harvard Medical School — both in Boston.
This article (10.1056/NEJMcpc0809065) was updated on September 30, 2009, at NEJM.org.
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