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A correction has been published: N Engl J Med 2009;361(14):1416.

Case Records of the Massachusetts General Hospital
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Volume 361:287-296 July 16, 2009 Number 3
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Case 22-2009 — A 59-Year-Old Man with Skin and Pulmonary Lesions after Chemotherapy for Leukemia
Thomas F. Patterson, M.D., Bonnie T. Mackool, M.D., Matthew D. Gilman, M.D., and Adriano Piris, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Presentation of Case

Dr. Deborah L. Cummins (Dermatology): A 59-year-old man was seen by consultants in infectious disease and dermatology because of cutaneous and pulmonary lesions that developed after induction chemotherapy for acute myeloid leukemia.

A diagnosis of myelodysplastic syndrome had been made 13 months earlier at another hospital. Since that time, the patient had been hospitalized repeatedly elsewhere for pancytopenia and had received transfusions of red cells and platelets. (The results of laboratory tests obtained 12 weeks before admission to this hospital are shown in Table 1.) Six weeks before admission to this hospital, the patient received azacitidine subcutaneously, followed 15 . . . [Full Text of this Article]

Differential Diagnosis

Bacterial Infections

Invasive Fungal Infections

Approach to Diagnosis and Initial Therapy

Clinical Diagnosis

Dr. Thomas F. Patterson's Diagnosis

Pathological Discussion

Anatomical Diagnosis


Source Information

From the Division of Infectious Diseases, University of Texas Health Science Center at San Antonio, and the South Texas Veterans Health Care System (T.F.P.) — both in San Antonio; and the Departments of Dermatology (B.T.M.), Radiology (M.D.G.), and Pathology (A.P.), Massachusetts General Hospital and Harvard Medical School — both in Boston.

This article (10.1056/NEJMcpc0809065) was updated on September 30, 2009, at NEJM.org.




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