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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 55-year-old man collapses while jogging through the park. A bystander finds him unconscious and without a pulse and initiates cardiopulmonary resuscitation (CPR) while an ambulance is summoned. On arrival in the emergency room, the patient is in ventricular fibrillation; the partial pressure of oxygen in arterial blood is 200 mm Hg, the pH is 7.25, and the bicarbonate level is 18
The Clinical Problem
Strategies and Evidence
Predictors of Outcome
Measures of Prognosis
Clinical Signs
Electrophysiological Signs
Biochemical Signs
Neuroimaging and Other Imaging
Ethical Considerations
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Departments of Clinical Neurological Sciences and Medicine, University of Western Ontario, London, ON, Canada.
An audio version of this article is available at NEJM.org.
Address reprint requests to Dr. Young at Rm. B10-106, University Hospital, 339 Windermere Rd., London, ON N6A 5A5, Canada, or at bryan.young@lhsc.on.ca.
Related Letters:
Neurologic Prognosis after Cardiac Arrest
Nesseler N., Leurent G., Seguin P., Grundmann S., Busch H.-J., Young G. B.
Extract |
Full Text |
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N Engl J Med 2009;
361:1999-2000, Nov 12, 2009.
Correspondence
This article has been cited by other articles:
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