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Editorial
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Volume 355:2149-2151 November 16, 2006 Number 20
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Treatment of In-Stent Restenosis — Back to the Future?
Edoardo Camenzind, M.D.

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Percutaneous transluminal coronary angioplasty has become the most frequently used method for myocardial revascularization.1 The use of uncoated coronary-artery stents during percutaneous intervention has decreased the incidence of acute complications and improved the outcome of patients,2 but restenosis within the stent compromises the long-term results. As a consequence, the prevention and treatment of in-stent restenosis have become priorities in interventional cardiology.

Drug-eluting stents, which markedly reduce in-stent restenosis,3 have relegated all other therapeutic approaches to the background. However, it is gradually emerging that rates of late restenosis after the use of drug-eluting stents are higher than initial experience suggested, particularly . . . [Full Text of this Article]


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From the Cardiology Department, University Hospital, Geneva.

This article was published at www.nejm.org on November 13, 2006.


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