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Published at www.nejm.org April 1, 2008 (10.1056/NEJMe0801992)

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Although it is difficult to study or even quantify, out-of-hospital cardiac arrest contributes greatly to total mortality in industrialized countries. Often such an event is the first manifestation of cardiovascular disease, and more than 90% of patients do not have identifiable high-risk characteristics. The estimated U.S. incidence of sudden cardiac arrest is 166,200 per year, with a median survival to hospital discharge of only 6.4%.¹

In this context, the automated external defibrillator (AED) has generated substantial hope. Clinical trials of the devices have gradually increased the scale of application from circumscribed locations, such as casinos and airplanes, to other public . . . [Full Text of this Article]

Source Information

From the Department of Medicine, Section of Cardiovascular Disease, University of Pennsylvania, Philadelphia.

This article (10.1056/NEJMe0801992) was published at www.nejm.org on April 1, 2008. It will appear in the April 24 issue of the Journal.

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