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Published at www.nejm.org November 25, 2009 (10.1056/NEJMopv0910749)

When to Consider the Use of Antibiotics in the Treatment of 2009 H1N1 Influenza–Associated Pneumonia

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We are now facing a pandemic caused by an epidemiologically distinct, novel virus, the 2009 pandemic influenza A (H1N1) virus (swine flu), against which few persons born since 1970 have antibodies. The severity of illness in the individual varies, and our understanding of the role of bacterial infection in novel 2009 H1N1 infection is still evolving. A current summary of bacterial isolates from 53 fatal pediatric cases of novel H1N1 with adequate sampling of normally sterile sites showed that 17 (32%) had bacterial pathogens of which 8 were Staphylococcus aureus, and of these, 6 were methicillin-resistant S. aureus (MRSA) (. . . [Full Text of this Article]



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