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Volume 356:981-984 March 8, 2007 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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After recognizing coronary drug-eluting stents as a "breakthrough technology" and granting them expedited review status, the Food and Drug Administration (FDA) approved two such devices for use in 2003 (Cordis's sirolimus-eluting Cypher stent) and 2004 (Boston Scientific's paclitaxel-eluting Taxus stent). Cardiologists quickly embraced the new technology; by the end of 2004, drug-eluting stents were used in nearly 80% of percutaneous coronary interventions in the United States, and within 3 years, several million drug-eluting stents had been implanted worldwide. Recently, however, concerns about an increased risk of late stent thrombosis have arisen and have been exacerbated by insufficient and conflicting information . . . [Full Text of this Article]

Source Information

Dr. Maisel is a cardiologist at Beth Israel Deaconess Medical Center and an assistant professor of medicine at Harvard Medical School — both in Boston. Dr. Maisel is also chair of the FDA Circulatory System Devices Advisory Panel.

This article (10.1056/NEJMp068305) was published at www.nejm.org on February 12, 2007.

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