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Viewing 1-20 of 3889683 Medline results for thisweek.asp;2
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Investigation of long-term retention of unchanged (-)-N-{2-[(R)-3-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidino]ethyl}-4-fluorobenzamide, a novel "funny" if current channel inhibitor, and its metabolites in the eyeball and thoracic aorta of rats.
K Umehara, N Nakada, K Noguchi, T Iwatsubo, T Usui, and H Kamimura
Drug Metab. Dispos.,
Nov 2009;
37:
2137-44.
Journal article
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Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC.
H Frederiksen, H Frandsen, and W Pfau
Carcinogenesis,
Aug 2004;
25:
1525-33.
Journal article
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The pulmonary physician in critical care * 2: oxygen delivery and consumption in the critically ill.
RM Leach and DF Treacher
Thorax,
Feb 2002;
57:
170-7.
Journal article
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Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in rat and human hepatocytes.
S Langouet, A Paehler, DH Welti, N Kerriguy, A Guillouzo, and RJ Turesky
Carcinogenesis,
Jan 2002;
23:
115-22.
Comparative study
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Phosphorylation of a bifunctional enzyme, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphate 2-phosphatase, is regulated physiologically and developmentally in rosette leaves of Arabidopsis thaliana.
T Furumoto, M Teramoto, N Inada, M Ito, I Nishida, and A Watanabe
Plant Cell Physiol.,
Oct 2001;
42:
1044-8.
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N-methyl-D-aspartate (NMDA) receptor NR2 subunit selectivity of a series of novel piperazine-2,3-dicarboxylate derivatives: preferential blockade of extrasynaptic NMDA receptors in the rat hippocampal CA3-CA1 synapse.
BM Costa, B Feng, TS Tsintsadze, RM Morley, MW Irvine, V Tsintsadze, NA Lozovaya, DE Jane, and DT Monaghan
J. Pharmacol. Exp. Ther.,
Nov 2009;
331:
618-26.
In vitro
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APD791, 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a novel 5-hydroxytryptamine 2A receptor antagonist: pharmacological profile, pharmacokinetics, platelet activity and vascular biology.
JW Adams, J Ramirez, Y Shi, W Thomsen, J Frazer, M Morgan, JE Edwards, W Chen, BR Teegarden, Y Xiong, H Al-Shamma, DP Behan, and DT Connolly
J. Pharmacol. Exp. Ther.,
Oct 2009;
331:
96-103.
Comparative study
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Tumorigenicity of four optically active bay-region 3,4-diol 1, 2-epoxides and other derivatives of the nitrogen heterocycle dibenz[c,h]acridine on mouse skin and in newborn mice.
RL Chang, AW Wood, S Kumar, RE Lehr, N Shirai, DM Jerina, and AH Conney
Carcinogenesis,
Nov 2000;
21:
1997-2003.
Comparative study
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Interaction of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/FBPase-2) with glucokinase activates glucose phosphorylation and glucose metabolism in insulin-producing cells.
L Massa, S Baltrusch, DA Okar, AJ Lange, S Lenzen, and M Tiedge
Diabetes,
Apr 2004;
53:
1020-9.
Journal article
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Potent carcinogenicity of 2,7-dinitrofluorene, an environmental pollutant, for the mammary gland of female Sprague-Dawley rats.
D Malejka-Giganti, GA Niehans, MA Reichert, KK Bennett, and RL Bliss
Carcinogenesis,
Oct 1999;
20:
2017-23.
Journal article
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Discriminative stimulus effects of 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane (DOM), ketanserin, and (R)-(+)-{alpha}-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-pipidinemethanol (MDL100907) in rats.
JX Li, A Unzeitig, MA Javors, KC Rice, W Koek, and CP France
J. Pharmacol. Exp. Ther.,
Nov 2009;
331:
671-9.
Journal article
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4-Hydroxy-2,2',3,4',5,5',6-heptachlorobiphenyl-mediated decrease in serum thyroxine level in mice occurs through increase in accumulation of thyroxine in the liver.
Y Kato, K Haraguchi, M Kubota, Y Seto, S Ikushiro, T Sakaki, N Koga, S Yamada, and M Degawa
Drug Metab. Dispos.,
Oct 2009;
37:
2095-102.
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Hemoglobin and DNA adducts in rats exposed to 2-nitrotoluene.
CR Jones, A Beyerbach, W Seffner, and G Sabbioni
Carcinogenesis,
Apr 2003;
24:
779-87.
Journal article
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Cav1.2 and Cav1.3 are differentially coupled to glucagon-like peptide-1 potentiation of glucose-stimulated insulin secretion in the pancreatic beta-cell line INS-1.
SM Jacobo, ML Guerra, and GH Hockerman
J. Pharmacol. Exp. Ther.,
Nov 2009;
331:
724-32.
Journal article
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Increased formation of hepatic N2-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase 2-knockout mice treated with ethanol.
T Matsuda, A Matsumoto, M Uchida, RA Kanaly, K Misaki, S Shibutani, T Kawamoto, K Kitagawa, KI Nakayama, K Tomokuni, and M Ichiba
Carcinogenesis,
Nov 2007;
28:
2363-6.
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Kinetic mechanism of quinol oxidation by cytochrome bd studied with ubiquinone-2 analogs.
Y Matsumoto, E Muneyuki, D Fujita, K Sakamoto, H Miyoshi, M Yoshida, and T Mogi
J. Biochem.,
Apr 2006;
139:
779-88.
Journal article
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Cryptogein-induced initial events in tobacco BY-2 cells: pharmacological characterization of molecular relationship among cytosolic Ca(2+) transients, anion efflux and production of reactive oxygen species.
Y Kadota, T Goh, H Tomatsu, R Tamauchi, K Higashi, S Muto, and K Kuchitsu
Plant Cell Physiol.,
Feb 2004;
45:
160-70.
Journal article
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Chemoprevention of 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine-induced colon carcinogenesis by 1-O-hexyl-2,3,5-trimethylhydroquinone after initiation with 1,2-dimethylhydrazine in F344 rats.
M Futakuchi, M Hirose, K Imaida, S Takahashi, K Ogawa, M Asamoto, T Miki, and T Shirai
Carcinogenesis,
Feb 2002;
23:
283-7.
Journal article
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N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
H Frandsen and J Alexander
Carcinogenesis,
Jun 2000;
21:
1197-203.
Journal article
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Urinary excretion of 2,7, 8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman is a major route of elimination of gamma-tocopherol in humans.
JE Swanson, RN Ben, GW Burton, and RS Parker
J. Lipid Res.,
Apr 1999;
40:
665-71.
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