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* This Week in the Journal
 January 31, 2008
 Audio Icon Audio Summary
*
Correspondence
* Hepatitis A Vaccine versus Immune Globulin for Postexposure Prophylaxis
* Children and the Quality of Ambulatory Care
* Hair Loss in Women
* Osteoarthritis of the Hip
* More on HIV-Associated Kaposi's Sarcoma
* Fluorodeoxyglucose PET in Relapsing Polychondritis
*
Book Reviews
* Proust and the Squid: The Story and Science of the Reading Brain
* Shyness: How Normal Behavior Became a Sickness
* Neurogenetic Developmental Disorders: Variation of Manifestation in Childhood
*
Continuing Medical Examination
* Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq
* Endovascular Repair of Abdominal Aortic Aneurysm
* Case 4-2008: A 33-Year-Old Pregnant Woman with Swelling of the Left Breast and Shortness of Breath
Original Articles
Mild Traumatic Brain Injuries in U.S. Soldiers Returning from Iraq

In this survey of soldiers who served in Iraq, about 15% reported concussions, also known as mild traumatic brain injuries (injuries resulting in brief loss of consciousness or confusion). Soldiers who had mild traumatic brain injuries were more likely to have post-traumatic stress disorder and physical health problems than were soldiers with other injuries.

Related Editorial


Original Articles
Endovascular vs. Open Repair of Abdominal Aortic Aneurysms

Endovascular repair is a less invasive strategy than open repair for the management of abdominal aortic aneurysm. This observational study in a large Medicare population shows that perioperative survival is superior with endovascular repair but that the survival advantage gradually wanes over 3 years. The survival advantage is more durable in older patients.


Original Articles
Cardiovascular Events during World Cup Soccer

This study documented an increased risk of cardiovascular events among viewers of highly competitive soccer matches during the 2006 World Cup finals in Germany. These data further establish the risk of cardiovascular events during stressful situations.


Special Article
Mortality from Violence in Iraq

In this national household survey, violence-related mortality in Iraq since the 2003 invasion was estimated to be 151,000 (95% confidence interval, 104,000 to 223,000). Although this estimate is lower than that in another recent report, it still indicates a massive death toll from violence in this war-torn country.

Related Perspective


Clinical Therapeutics
Endovascular Repair of Abdominal Aortic Aneurysm

A 72-year-old man is found to have an abdominal aortic aneurysm that is 5.7 cm in diameter, and endovascular repair is considered. The use of an abdominal aortic stent–graft for repair of an abdominal aortic aneurysm is associated with lower early mortality than open surgical repair but also with a higher risk of subsequent need for reintervention and with a less certain long-term outcome.


Review Article
Molecular Origins of Cancer: Oncogenes and Cancer

This review — the first in a series concerning the biology of cancer — is a comprehensive survey of oncogenes, tumor-suppressor genes, and microRNA genes in cancer cells. Work on the recently discovered microRNA genes in malignant cells has revealed new complexities in the regulation of oncogenes and tumor-suppressor genes and new opportunities for the treatment of cancer.

Related Editorial


Case Records of the Massachusetts General Hospital
A 33-Year-Old Pregnant Woman with Swelling of the Left Breast and Shortness of Breath

A 33-year-old pregnant woman was admitted to the hospital at 30.7 weeks' gestation because of swelling of the left breast, shortness of breath, and tachycardia. The swelling of the left breast had developed at 26.1 weeks' gestation and did not improve with antibiotic treatment. Ultrasonography and mammography showed enlargement of the left breast with increased density and no masses. A biopsy was performed. Shortness of breath developed, and the patient was admitted to the hospital. Computed tomography of the chest disclosed a large mediastinal mass.


Clinical Implications of Basic Research
Understanding Inflammatory Bowel Disease

Experiments on genetically engineered mice indicate that perimucosal tumor necrosis factor {alpha} influences the development of microflora associated with inflammatory bowel disease.


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